abstract：BACKGROUND AND PURPOSE:The CHA2DS2-VASc score aims to improve risk stratification of ischemic stroke among patients with atrial fibrillation to identify those who can safely forego oral anticoagulation. Oral anticoagulation treatment guidelines remain uncertain for CHA2DS2-VASc score of 1. We conducted a systematic rev...

journal_title：Stroke

authors： Joundi RA,Cipriano LE,Sposato LA,Saposnik G,Stroke Outcomes Research Working Group.

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke-associated immunosuppression is an increasingly recognized factor triggering infections and thus potentially influencing outcome after stroke. Specifically, lymphocytopenia after intracerebral hemorrhage (ICH) has only been addressed in small-sized retrospective studies of mixed intracrani...

journal_title：Stroke

authors： Giede-Jeppe A,Bobinger T,Gerner ST,Madžar D,Sembill J,Lücking H,Kloska SP,Keil T,Kuramatsu JB,Huttner HB

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:It is unclear whether anxiety is a risk factor for stroke. We assessed the association between anxiety and the risk of incident stroke. METHODS:This population-based cohort study was based on 2 rounds of the Rotterdam Study. Each round was taken separately as baseline. In 1993 to 1995, anxiety s...

journal_title：Stroke

authors： Portegies ML,Bos MJ,Koudstaal PJ,Hofman A,Tiemeier HW,Ikram MA

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke on board aircraft has been reported in retrospective case series, mainly focusing on economy class stroke syndrome. Data on the actual incidence, pathogenesis, and prognosis of stroke in commercial flights are lacking. METHODS:A prospective registry was designed to include all consecutive...

journal_title：Stroke

authors： Álvarez-Velasco R,Masjuan J,DeFelipe A,Corral I,Estévez-Fraga C,Crespo L,Alonso-Cánovas A

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Follow-up imaging is often performed in intracranial aneurysms that are not treated. We performed a systematic review and meta-analysis on patient- and aneurysm-specific risk factors for aneurysm growth. METHODS:We searched EMBASE and MEDLINE for cohort studies describing risk factors for aneury...

journal_title：Stroke

authors： Backes D,Rinkel GJ,Laban KG,Algra A,Vergouwen MD

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke and systemic embolic events are known to occur as complications of hypertrophic cardiomyopathy (HCM), and these complications are more common in patients with accompanying atrial fibrillation (AF). The diagnosis of AF is sometimes difficult, however, and it is possible that subclinical asy...

journal_title：Stroke

authors： Haruki S,Minami Y,Hagiwara N

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and is linked with mortality, cardiovascular events, and stroke. However, the role of FGF23 as a risk factor for subclinical cerebrovascular damage is unclear. METHODS:We used multivariable linear and logistic regressio...

journal_title：Stroke

authors： Wright CB,Shah NH,Mendez AJ,DeRosa JT,Yoshita M,Elkind MS,Sacco RL,DeCarli C,Rundek T,Silverberg S,Dong C,Wolf M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral hemorrhage is uncertain. We determined associations of computed tomographic radiological manifestations...

journal_title：Stroke

authors： Sato S,Delcourt C,Heeley E,Arima H,Zhang S,Al-Shahi Salman R,Stapf C,Woo D,Flaherty ML,Vagal A,Levi C,Davies L,Wang J,Robinson T,Lavados PM,Lindley RI,Chalmers J,Anderson CS,INTERACT2 Investigators.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Our aim was to explore whether the mismatch in lesion visibility between b1000 and b0 images is an alternative to mismatch between diffusion-weighted imaging and fluid-attenuated inversion recovery imaging as a surrogate marker of stroke age. METHODS:We analyzed patients from the European multic...

journal_title：Stroke

authors： Geraldo AF,Berner LP,Haesebaert J,Chabrol A,Cho TH,Derex L,Hermier M,Louis-Tisserand G,Chamard L,Klaerke Mikkelsen I,Ribe L,Østergaard L,Hjort N,Pedraza S,Thomalla G,Baron JC,Nighoghossian N,Berthèzene Y

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite rapid advancements in intracranial aneurysm management, there is no evidence as of yet that this has translated into improvement in overall prognosis. METHODS:We compared 2 periods of aneurysm management, 1998 to 2003 (n=1023 aneurysms) and 2007 to 2013 (n=1499 aneurysms), at a single, h...

journal_title：Stroke

authors： Chua MH,Griessenauer CJ,Stapleton CJ,He L,Thomas AJ,Ogilvy CS

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Whether newly diagnosed atrial fibrillation (nAF) after stroke reflects underlying heart disease and represents an increased risk of cardioembolic stroke, or whether it is triggered by neurogenic mechanisms remains uncertain. We investigated, whether cardiovascular risk factors and echocardiograp...

journal_title：Stroke

authors： Rizos T,Horstmann S,Dittgen F,Täger T,Jenetzky E,Heuschmann P,Veltkamp R

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The ankle-brachial index (ABI) is a fast, cheap, noninvasive indicator of atherosclerotic burden that may also be a predictor of stroke recurrence. In this systematic review and meta-analysis, we sought to explore ABI's merit as a marker for stroke recurrence and vascular risk by synthesizing the...

journal_title：Stroke

authors： Hong JB,Leonards CO,Endres M,Siegerink B,Liman TG

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Three-dimensional pseudocontinuous arterial spin labeling with multiple postlabeling delays has been used to assess cerebral blood flow (CBF). We used this modality to estimate antegrade and collateral flow in patients with unilateral middle cerebral artery stenosis. METHODS:Consecutive patients...

journal_title：Stroke

authors： Lyu J,Ma N,Liebeskind DS,Wang DJ,Ma L,Xu Y,Wang T,Miao Z,Lou X

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although a genetic contribution to ischemic stroke is well recognized, only a handful of stroke loci have been identified by large-scale genetic association studies to date. Hypothesizing that genetic effects might be stronger for early- versus late-onset stroke, we conducted a 2-stage meta-analy...

journal_title：Stroke

authors： Cheng YC,Stanne TM,Giese AK,Ho WK,Traylor M,Amouyel P,Holliday EG,Malik R,Xu H,Kittner SJ,Cole JW,O'Connell JR,Danesh J,Rasheed A,Zhao W,Engelter S,Grond-Ginsbach C,Kamatani Y,Lathrop M,Leys D,Thijs V,Metso TM,

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Apraxia of speech (AOS) is a motor speech disorder, which is clinically characterized by the combination of phonemic segmental changes and articulatory distortions. AOS has been believed to arise from impairment in motor speech planning/programming and differentiated from both aphasia and dysarth...

journal_title：Stroke

authors： Itabashi R,Nishio Y,Kataoka Y,Yazawa Y,Furui E,Matsuda M,Mori E

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial artery dolichoectasia (IADE) and coronary artery ectasia have been associated with stroke and myocardial infarction, respectively. Only rarely have cases of coexisting IADE and coronary artery ectasia been reported. We investigated this association in a large consecutive autopsy seri...

journal_title：Stroke

authors： Pico F,Labreuche J,Hauw JJ,Seilhean D,Duyckaerts C,Amarenco P

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Questionnaire for Verifying Stroke-Free Status (QVSFS), a method for verifying stroke-free status in participants of clinical, epidemiological, and genetic studies, has not been validated in low-income settings where populations have limited knowledge of stroke symptoms. We aimed to validate ...

journal_title：Stroke

authors： Sarfo F,Gebregziabher M,Ovbiagele B,Akinyemi R,Owolabi L,Obiako R,Akpa O,Armstrong K,Akpalu A,Adamu S,Obese V,Boa-Antwi N,Appiah L,Arulogun O,Mensah Y,Adeoye A,Tosin A,Adeleye O,Tabi-Ajayi E,Phillip I,Sani A,Isa

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Stroke-induced neuroinflammation and white matter damage are associated with neurological deficits. Whether D-4F, an apolipoprotein A-I mimetic peptide, treatment of stroke decreases neuroinflammation and white matter damage and improves functional outcome has not been investigated. METHODS:Adul...

journal_title：Stroke

authors： Cui X,Chopp M,Zacharek A,Cui C,Yan T,Ning R,Chen J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:We systematically compared and appraised contemporary guidelines on management of asymptomatic and symptomatic carotid artery stenosis. METHODS:We systematically searched for guideline recommendations on carotid endarterectomy (CEA) or carotid angioplasty/stenting (CAS) published in any language...

journal_title：Stroke

authors： Abbott AL,Paraskevas KI,Kakkos SK,Golledge J,Eckstein HH,Diaz-Sandoval LJ,Cao L,Fu Q,Wijeratne T,Leung TW,Montero-Baker M,Lee BC,Pircher S,Bosch M,Dennekamp M,Ringleb P

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Perihematomal edema (PHE) is associated with poor outcomes after intracerebral hemorrhage (ICH). PHE evolves in the early period after ICH, providing a therapeutic target and window for intervention. We studied the effect of PHE volume expansion in the first 72 hours (iPHE) and its relationship w...

journal_title：Stroke

authors： Murthy SB,Moradiya Y,Dawson J,Lees KR,Hanley DF,Ziai WC,VISTA-ICH Collaborators.

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:National Institutes of Health Stroke Scale (NIHSS) item profiles that were recently proposed and validated may prove useful for clinical prognostication and research studies. We aimed to validate the NIHSS item profiles in hyper-acute stroke patients who received thrombolysis treatment (tissue-ty...

journal_title：Stroke

authors： Abdul-Rahim AH,Fulton RL,Sucharew H,Kleindorfer D,Khatri P,Broderick JP,Lees KR,SITS-MOST Steering Committee.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid angioplasty and stenting (CAS) is associated with higher risk of periprocedural stroke and death when compared with carotid endarterectomy (CEA). By contrast, the risk of myocardial infarction (MI) was higher after CEA than after CAS in randomized trials. However, numbers were small, and ...

journal_title：Stroke

authors： Boulanger M,Camelière L,Felgueiras R,Berger L,Rerkasem K,Rothwell PM,Touzé E

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Emergency medical services routing of patients with acute stroke to designated centers may increase the proportion of patients receiving care at facilities meeting national standards and augment recruitment for prehospital stroke research. METHODS:We analyzed consecutive patients enrolled within...

journal_title：Stroke

authors： Sanossian N,Liebeskind DS,Eckstein M,Starkman S,Stratton S,Pratt FD,Koenig W,Hamilton S,Kim-Tenser M,Conwit R,Saver JL,FAST-MAG Investigators and Coordinators.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The Stroke Health and Risk Education Project was a cluster-randomized, faith-based, culturally sensitive, theory-based multicomponent behavioral intervention trial to reduce key stroke risk factor behaviors in Hispanics/Latinos and European Americans. METHODS:Ten Catholic churches were randomize...

journal_title：Stroke

authors： Brown DL,Conley KM,Sánchez BN,Resnicow K,Cowdery JE,Sais E,Murphy J,Skolarus LE,Lisabeth LD,Morgenstern LB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The purpose was to investigate the occurrence of self-reported falls in people with stroke at 3, 6, and 12 months and 6 years post stroke and predictors for falls during 6 years. METHODS:A prospective study involving 121 people with stroke. Data were obtained through structured interviews and as...

journal_title：Stroke

authors： Minet LR,Peterson E,von Koch L,Ytterberg C

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In primary intracerebral hemorrhage, the presence of contrast extravasation after computed tomographic angiography (CTA), termed the spot sign, predicts hematoma expansion and mortality. Because the biological underpinnings of the spot sign are not fully understood, we investigated whether the ra...

journal_title：Stroke

authors： Brouwers HB,Battey TW,Musial HH,Ciura VA,Falcone GJ,Ayres AM,Vashkevich A,Schwab K,Viswanathan A,Anderson CD,Greenberg SM,Pomerantz SR,Ortiz CJ,Goldstein JN,Gonzalez RG,Rosand J,Romero JM

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Venous thromboembolism and ischemic stroke are associated with unfavorable fibrin clot structure and function. We hypothesized that denser fibrin networks displaying impaired lysability characterize patients with cerebral venous sinus thrombosis (CVST). METHODS:We assessed plasma fibrin clot pro...

journal_title：Stroke

authors： Siudut J,Świat M,Undas A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Futile recanalization after acute ischemic stroke occurs in almost half of the patients despite optimal angiographic results. Multimodal neuroimaging may help to improve patient's selection but is still dismissed by many interventionalists. Our aim was to evaluate the accuracy of each parameter o...

journal_title：Stroke

authors： Espinosa de Rueda M,Parrilla G,Manzano-Fernández S,García-Villalba B,Zamarro J,Hernández-Fernández F,Sánchez-Vizcaino C,Carreón E,Morales A,Moreno A

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Intracranial internal carotid artery calcification is associated with cerebrovascular risk factors and stroke, but few quantification methods are available. We tested the reliability of visual scoring, semiautomated Agatston score, and calcium volume measurement in patients with recent stroke. M...

journal_title：Stroke

authors： Subedi D,Zishan US,Chappell F,Gregoriades ML,Sudlow C,Sellar R,Wardlaw J

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Transorbital sonography may help establish diagnosis of central retinal artery occlusion (CRAO). Next to Doppler sonographic proof of CRAO, an intra-arterial spot sign can be detected in some cases. We hypothesized that it reflects calcified components. It may be associated with embolization from...

journal_title：Stroke

authors： Nedelmann M,Graef M,Weinand F,Wassill KH,Kaps M,Lorenz B,Tanislav C

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Monocytes may contribute to secondary injury after intracerebral hemorrhage (ICH). We tested the association of absolute monocyte count with 30-day ICH case fatality in a multiethnic cohort. METHODS:Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study is a prospective, multicenter,...

journal_title：Stroke

authors： Walsh KB,Sekar P,Langefeld CD,Moomaw CJ,Elkind MS,Boehme AK,James ML,Osborne J,Sheth KN,Woo D,Adeoye O

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Failure to recanalize predicts mortality in acute ischemic stroke. In the North American Solitaire Acute Stroke registry, we investigated parameters associated with mortality in successfully recanalized patients. METHODS:Logistic regression was used to evaluate baseline characteristics and recan...

journal_title：Stroke

authors： Linfante I,Walker GR,Castonguay AC,Dabus G,Starosciak AK,Yoo AJ,Abou-Chebl A,Britz GW,Marden FA,Alvarez A,Gupta R,Sun CH,Martin C,Holloway WE,Mueller-Kronast N,English JD,Malisch TW,Bozorgchami H,Xavier A,Rai AT,F

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although the modified Rankin Scale (mRS) is the most commonly used primary end point in acute stroke trials, its power is limited when analyzed in dichotomized fashion and its indication of effect size challenging to interpret when analyzed ordinally. Weighting the 7 Rankin levels by utilities ma...

journal_title：Stroke

authors： Chaisinanunkul N,Adeoye O,Lewis RJ,Grotta JC,Broderick J,Jovin TG,Nogueira RG,Elm JJ,Graves T,Berry S,Lees KR,Barreto AD,Saver JL,DAWN Trial and MOST Trial Steering Committees.,Additional contributors from DAWN Trial Steering

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Early hematoma growth is not uncommon in patients with intracerebral hemorrhage and is an independent predictor of poor functional outcome. The purpose of our study was to report and validate the use of our newly identified computed tomographic (CT) blend sign in predicting early hematoma growth....

journal_title：Stroke

authors： Li Q,Zhang G,Huang YJ,Dong MX,Lv FJ,Wei X,Chen JJ,Zhang LJ,Qin XY,Xie P

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Elevated soluble CD40 ligand (sCD40L) was shown to be related to cardiovascular events, but the role of sCD40L in predicting recurrent stroke remains unclear. METHODS:Baseline sCD40L levels were measured in 3044 consecutive patients with acute minor stroke and transient ischemic attack, who had ...

journal_title：Stroke

authors： Li J,Wang Y,Lin J,Wang D,Wang A,Zhao X,Liu L,Wang C,Wang Y,CHANCE Investigators.

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Little is known about how regions vary in their use of thrombolysis (intravenous tissue-type plasminogen activator and intra-arterial treatment) for acute stroke. We sought to determine regional variation in thrombolysis treatment and investigate the extent to which regional variation is accounte...

journal_title：Stroke

authors： Skolarus LE,Meurer WJ,Shanmugasundaram K,Adelman EE,Scott PA,Burke JF

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prevalence of cerebral microbleeds (CMB) in white and Asian populations range from 4% to 15%. However, there is no information from indigenous Latin American people. We aimed to assess prevalence and cerebrovascular correlates of CMB in stroke-free older adults living in rural Ecuador. METHODS:O...

journal_title：Stroke

authors： Del Brutto VJ,Zambrano M,Mera RM,Del Brutto OH

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Recovery of patients within the first 6 months after stroke is well documented, but there has been little research on long-term recovery. The aim of this study was to analyze functional and motor recovery between admission to rehabilitation centres and 5 years after stroke. METHODS:This follow-u...

journal_title：Stroke

authors： Meyer S,Verheyden G,Brinkmann N,Dejaeger E,De Weerdt W,Feys H,Gantenbein AR,Jenni W,Laenen A,Lincoln N,Putman K,Schuback B,Schupp W,Thijs V,De Wit L

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sulcal effacement with preserved underlying gray-white matter junction (isolated sulcal effacement [ISE]) in acute ischemic stroke may not represent irreversible parenchymal injury. We aimed to evaluate the frequency and significance of ISE in patients with large vessel occlusion acute ischemic s...

journal_title：Stroke

authors： Haussen DC,Lima A,Frankel M,Anderson A,Belagaje S,Nahab F,Rangaraju S,Nogueira RG

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Although left atrial enlargement (LAE) increases incident stroke risk, the association with recurrent stroke is less clear. Our aim was to determine the association of LAE with recurrent stroke most likely related to embolism (cryptogenic and cardioembolic) and all ischemic stroke recurrences. M...

journal_title：Stroke

authors： Yaghi S,Moon YP,Mora-McLaughlin C,Willey JZ,Cheung K,Di Tullio MR,Homma S,Kamel H,Sacco RL,Elkind MS

更新日期：2015-06-01 00:00:00